GO:0033176 cellular_component proton-transporting V-type ATPase complex
| PAG Title | GO:0033176 cellular_component proton-transporting V-type ATPase complex |
| PAG ID | TAX022017 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane. |
| Species | Homo sapiens |
| nCoCo Score | 2,388 |
| Base PAG ID | TAX022017 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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